CHDI
Listed here are over 1,060 publications that describe some of the research funded (in whole or in part) by CHDI Foundation. You can also view just the subset of publications that have CHDI staff as authors.
Publication Search
Title
Journal
Wetzel HH, Gehl CR, Dellefave-Castillo L, Schiffman JF, Shannon KM, Paulsen JS, Huntington Study Group
Suicidal ideation in Huntington disease: the role of comorbidity
van den Bogaard SJ, Dumas EM, Ferrarini L, Milles J, van Buchem MA, van der Grond J, Roos RA
Shape analysis of subcortical nuclei in Huntington`s disease, global versus local atrophy--results from the TRACK-HD study
Zuccato C, Marullo M, Vitali B, Tarditi A, Mariotti C, Valenza M, Lahiri N, Wild EJ, Sassone J, Ciammola A, Bachoud-Lèvi AC, Tabrizi SJ, Di Donato S, Cattaneo E
Brain-derived neurotrophic factor in patients with Huntington's disease
Williams J, Downing N, Vaccarino AL, Guttman M, Paulsen JS
Self reports of day-to-day function in a small cohort of people with prodromal and early HD
Hobbs NZ, Pedrick AV, Say MJ, Frost C, Dar Santos R, Coleman A, Sturrock A, Craufurd D, Stout JC, Leavitt BR, Barnes J, Tabrizi SJ, Scahill RI
The structural involvement of the cingulate cortex in premanifest and early Huntington`s disease
Ready RE, O’Rourke JJ, Paulsen JS
Quality of life in prodromal HD: Qualitative analyses of discourse from participants and companions
Muller I, Lamers MB, Ritchie AJ, Park H, Dominguez C, Munoz-Sanjuan I, Maillard M, Kiselyov A
A new apo-caspase-6 crystal form reveals the active conformation of the apoenzyme
Reinhart PH, Kaltenbach LS, Essrich C, Dunn DE, Eudailey JA, DeMarco CT, Turmel GJ, Whaley JC, Wood A, Cho S, Lo DC
Identification of anti-inflammatory targets for Huntington's disease using a brain slice-based screening assay
Williams RH, Morton AJ, Burdakov D
Paradoxical function of orexin/hypocretin circuits in a mouse model of Huntington's disease
O`Rourke JJ, Beglinger LJ, Smith MM, Mills J, Moser DJ, Rowe KC, Langbehn DR, Duff K, Stout JC, Harrington DL, Carlozzi N, Paulsen JS
The Trail Making Test in prodromal Huntington disease: contributions of disease progression to test performance
Vaccarino AL, Anderson K, Borowsky B, Duff K, Giuliano J, Guttman M, Ho AK, Orth M, Paulsen JS, Sills T, van Kammen DP, Evans KR, Predict HD and Registry Investigators Coordinators
An item response analysis of the motor and behavioral subscales of the unified Huntington`s disease rating scale in huntington disease gene expansion carriers
Aylward EH, Nopoulos PC, Ross CA, Langbehn DR, Pierson RK, Mills JA, Johnson HJ, Magnotta VA, Juhl AR, Paulsen JS, Predict-HD Investigators and Coordinators of Huntington Study Group
Longitudinal change in regional brain volumes in prodromal Huntington disease
van den Bogaard SJ, Dumas EM, Acharya TP, Johnson H, Langbehn DR, Scahill RI, Tabrizi SJ, van Buchem MA, van der Grond J, Roos RA, TRACK-HD Investigator Group
Early atrophy of pallidum and accumbens nucleus in Huntington's disease
Kudo T, Schroeder A, Loh DH, Kuljis D, Jordan MC, Roos KP, Colwell CS
Dysfunctions in circadian behavior and physiology in mouse models of Huntington's disease
Duzdevich D, Li J, Whang J, Takahashi H, Takeyasu K, Dryden DT, Morton AJ, Edwardson JM
Unusual structures are present in DNA fragments containing super-long Huntingtin CAG repeats
Sah DW, Aronin N
Oligonucleotide therapeutic approaches for Huntington disease
Eidelberg D, Surmeier DJ
Brain networks in Huntington disease
Munoz-Sanjuan I, Bates GP
The importance of integrating basic and clinical research toward the development of new therapies for Huntington disease
J Clin Invest
February 1, 2011
121 (2) :476-83
121 (2) :476-83
PMID: 21285520
PMCID: PMC3026740
DOI: 10.1172/JCI45364
Tabrizi SJ, Scahill RI, Durr A, Roos RA, Leavitt BR, Jones R, Landwehrmeyer GB, Fox NC, Johnson H, Hicks SL, Kennard C, Craufurd D, Frost C, Langbehn DR, Reilmann R, Stout JC, TRACK-HD Investigators
Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis
Morse RJ, Leeds JM, Macdonald D, Park L, Toledo-Sherman L, Pacifici R
Pharmaceutical development for Huntington’s disease. In: Neurobiology of Huntington's disease: Applications to drug discovery
Neurobiology of Huntington's Disease
January 1, 2011
8
8
PMID: 21882420
Oakeshott S, Port RG, Cummins-Sutphen J, Watson-Johnson J, Ramboz S, Park L, Howland D, Brunner D
HD mouse models reveal clear deficits in learning to perform a simple instrumental response
Vaccarino AL, Sills T, Anderson KE, Borowsky B, Craufurd D, Giuliano J, Goodman L, Guttman M, Kupchak P, Ho AK, Paulsen JS, Stout J, van Kammen DP, Evans K
Assessment of cognitive symptoms in prodromal and early huntington disease
Vaccarino AL, Sills T, Anderson KE, Endicott J, Giuliano J, Guttman M, Ho AK, Kupchak P, Paulsen JS, Warner JH, Williams J, Evans K
Assessment of day-to-day functioning in prodromal and early Huntington Disease
Vaccarino AL, Anonymous, Anderson KE, Borowsky B, Coccaro E, Craufurd D, Endicott J, Giuliano J, Groves M, Guttman M, Ho AK, Kupchak P, Paulsen JS, Stanford MS, van Kammen DP, Watson D, Wu KD, Evans K
Assessing behavioural manifestations prior to clinical diagnosis of huntington disease: "anger and irritability" and "obsessions and compulsions"
Vaccarino AL, Sills T, Anderson KE, Biglan K, Borowsky B, Giuliano J, Guttman M, Ho AK, Kennard C, Kupchak P, Landwehrmeyer GB, Michell A, Paulsen JS, Reilmann R, van Kammen DP, Warner JH, Evans K
Assessment of motor symptoms and functional impact in prodromal and early huntington disease
Vaccarino AL, Sills T, Anderson KE, Bachoud-Levi AC, Borowsky B, Craufurd D, Duff K, Giuliano J, Groves M, Guttman M, Kupchak P, Ho AK, Paulsen JS, Pedersen KF, van Duijn E, van Kammen DP, Evans K
Assessment of depression, anxiety and apathy in prodromal and early huntington disease
Fiedorowicz JG, Mills JA, Ruggle A, Langbehn D, Paulsen JS, Predict-Hd Investigators of the Huntington Study Group
Suicidal behavior in prodromal Huntington disease
Neurodegener Dis
January 1, 2011
8 (6) :483-90
8 (6) :483-90
PMID: 21659725
PMCID: PMC3186721
DOI: 10.1159/000327754
Aylward E, Mills J, Liu D, Nopoulos P, Ross CA, Pierson R, Paulsen JS
Association between Age and Striatal Volume Stratified by CAG Repeat Length in Prodromal Huntington Disease
Oakeshott S, Balci F, Filippov I, Murphy C, Port R, Connor D, Paintdakhi A, Lesauter J, Menalled L, Ramboz S, Kwak S, Howland D, Silver R, Brunner D
Circadian abnormalities in motor activity in a BAC transgenic mouse model of Huntington`s Disease
Say MJ, Jones R, Scahill RI, Dumas EM, Coleman A, Santos RC, Justo D, Campbell JC, Queller S, Shores EA, Tabrizi SJ, Stout JC, Track-Hd Investigators
Visuomotor integration deficits precede clinical onset in Huntington`s disease
Neuropsychologia
January 1, 2011
49 (2) :264-70
49 (2) :264-70
PMID: 21094653
Nopoulos PC, Aylward EH, Ross CA, Mills JA, Langbehn DR, Johnson HJ, Magnotta VA, Pierson RK, Beglinger LJ, Nance MA, Barker RA, Paulsen JS, Predict-Hd Investigators, Coordinators of the Huntington Study Group
Smaller intracranial volume in prodromal Huntington`s disease: evidence for abnormal neurodevelopment
Stout JC, Paulsen JS, Queller S, Solomon AC, Whitlock KB, Campbell JC, Carlozzi N, Duff K, Beglinger LJ, Langbehn DR, Johnson SA, Biglan KM, Aylward EH
Neurocognitive signs in prodromal Huntington disease
Neuropsychology
January 1, 2011
25 (1) :43844
25 (1) :43844
PMID: 20919768
PMCID: PMC3017660
DOI: 10.1037/a0020937
Nopoulos PC, Aylward EH, Ross CA, Johnson HJ, Magnotta VA, Juhl AR, Pierson RK, Mills J, Langbehn DR, Paulsen JS, Predict-Hd Investigators Coordinators of Huntington Study Group
Cerebral cortex structure in prodromal Huntington disease
Soneson C, Fontes M, Zhou Y, Denisov V, Paulsen JS, Kirik D, Petersen A, Huntington Study Group Predict-HD Investigators
Early changes in the hypothalamic region in prodromal Huntington disease revealed by MRI analysis
Leyva MJ, Degiacomo F, Kaltenbach LS, Holcomb J, Zhang N, Gafni J, Park H, Lo DC, Salvesen GS, Ellerby LM, Ellman JA
Identification and evaluation of small molecule pan-caspase inhibitors in Huntington`s disease models
Paulsen JS, Wang C, Duff K, Barker R, Nance M, Beglinger L, Moser D, Williams JK, Simpson S, Langbehn D, van Kammen DP, Predict-Hd Investigators of the Huntington Study Group
Challenges assessing clinical endpoints in early Huntington disease
Mov Disord
November 15, 2010
25 (15) :2595-603
25 (15) :2595-603
PMID: 20623772
PMCID: PMC2978744
DOI: 10.1002/mds.23337
Graham RK, Deng Y, Carroll J, Vaid K, Cowan C, Pouladi MA, Metzler M, Bissada N, Wang L, Faull RL, Gray M, Yang XW, Raymond LA, Hayden MR
Cleavage at the 586 amino acid caspase-6 site in mutant huntingtin influences caspase-6 activation in vivo
Goodman AO, Morton AJ, Barker RA
Identifying sleep disturbances in Huntington's disease using a simple disease-focused questionnaire
Orth M, Handley OJ, Schwenke C, Dunnett SB, Craufurd D, Ho AK, Wild E, Tabrizi SJ, Landwehrmeyer GB, Investigators of the European Huntington’s Disease Network
Observing Huntington's disease: the European Huntington's Disease Network's REGISTRY
Marrakchi-Kacem L, Delmaire C, Tucholka A, Roca P, Guevara P, Poupon F, Yelnik J, Durr A, Mangin JF, Lehericy S, Poupon C
Analysis of the striato-thalamo-cortical connectivity on the cortical surface to infer biomarkers of Huntington's disease
Med Image Comput Comput Assist
September 20, 2010
13 :217-24
13 :217-24
PMID: 20879318