Independent Statistical Standing Committee

Independent Statistical Standing Committee

The Independent Statistical Standing Committee (ISSC) is intended to provide independent, unbiased evaluation and expert advice regarding all aspects of experimental design and statistics. Its overarching aim is to help improve the quality and reproducibility of scientific research and, as such, CHDI is making this resource available to the Huntington’s disease research community on a priority basis. The ISSC is comprised of individuals from a diverse range of disciplines with specific expertise in research design and statistics. Critically, committee members are not themselves engaged in Huntington’s disease research, mitigating any potential biases.

Services:

The ISSC provides a number of services, including:

  • Experimental design assistance;
  • Sample size / power calculations;
  • Advice on statistical methods;
  • Methodological evaluation of published research;
  • Educational resource development.

Committee members:

There are currently seven members of the ISSC, each with a special interest in scientific rigor and study reproducibility. New members may be invited onto the ISSC to cover new methodologies, or affiliates consulted for specific projects.

Name

Affiliation

Position

Marcus Munafò (Chair) University of Bristol Professor of Biological Psychology
William Browne University of Bristol Professor of Statistics
Stan Lazic Prioris.ai Inc. Co-founder and Chief Scientific Officer
Glyn Lewis University College London Professor of Psychiatric Epidemiology
Martin Lindquist Johns Hopkins University Professor of Biostatistics
Malcolm MacLeod University of Edinburgh Professor of Neurology and Translational Neurosciences
Eric-Jan Wagenmakers University of Amsterdam Professor of Neurocognitive Modeling

Engagement:

Jen Ware, PhD (jennifer.ware@chdifoundation.org), Director, Experimental Design at CHDI, is the point of contact for engagement with the ISSC. Please contact her directly to discuss your requirements.

Process: