CHDI
2019
Authors
Title
Journal
- Huguet G, | Temel Y, | Kádár E, | Pol S, | Casaca-Carreira J, | Segura-Torres P, | Jahanshahi A |Altered expression of dopaminergic cell fate regulating genes prior to manifestation of symptoms in a transgenic rat model of Huntington's diseaseBrain Res101-1081712():20190601PMID:30711400Dvorzhak A, | Helassa N, | Török K, | Schmitz D, | Grantyna R |Single synapse indicators of impaired glutamate clearance derived from fast iGlu u imaging of cortical afferents in the striatum of normal and Huntington (Q175) miceJ Neurosci3970-398239(20):20190515PMID:30819797Svedberg MM, | Varnäs K, | Varrone A, | Mitsios N, | Mulder J, | Gulyás B, | Beaumont V, | Munoz-Sanjuan I, | Zaleska MM, | Schmidt CJ, | Halldin C, | Mrzljak L |In vitro phosphodiesterase 10A (PDE10A) binding in whole hemisphere human brain using the PET radioligand [(18)F] MNI-659Brain Res140-1451711():20190515PMID:30664847Sharma M, | Subramaniam S |Rhes travels from cell to cell and transports Huntington disease protein via TNT-like protrusionJ Cell Biolpii: jcb.201807068():20190510PMID:31076452Di Marco A, | Gonzalez Paz O, | Fini I, | Vignone D, | Cellucci A, | Battista MR, | Auciello G, | Orsatti L, | Zini M, | Monteagudo E, | Khetarpal V, | Rose M, | Dominguez C, | Herbst T, | Toledo-Sherman L, | Summa V, | Muñoz-Sanjuán I |Application of an in vitro blood-brain barrier model in the selection of experimental drug candidates for the treatment of Huntington's diseaseMol Pharm2069-208216(5):20190506PMID:30916978Kojer K, | Hering T, | Bazenet C, | Weiss A, | Herrmann F, | Taanman JW, | Orth M |Huntingtin aggregates and mitochondrial pathology in skeletal muscle but not heart of late-stage R6/2 miceJ Huntingtons Dis145–1598(2):20190430PMID:30814364DOI: 10.3233/JHD-180324Harding RJ, | Loppnau P, | Ackloo S, | Lemak A, | Hutchinson A, | Hunt B, | Holehouse AS, | Ho JC, | Fan L, | Toledo-Sherman L, | Seitova A, | Arrowsmith CH |Design and characterization of mutant and wildtype huntingtin proteins produced from a toolkit of scalable eukaryotic expression systemsJ Biol Chem6986-7001294(17):20190426PMID:30842263Carrillo-Reid L, | Day M, | Xie Z, | Melendez AE, | Kondapalli J, | Plotkin JL, | Wokosin DL, | Chen Y, | Kress GJ, | Kaplitt M, | Ilijic E, | Guzman JN, | Chan SS, | Surmeier DJ |Mutant huntingtin enhances activation of dendritic Kv4 K(+) channels in striatal spiny projection neuronsElifee408188():20190424PMID:31017573DOI: 10.7554/eLife.40818Espinoza FA, | Liu J, | Ciarochi J, | Turner JA, | Vergara VM, | Caprihan A, | Misiura M, | Johnson HJ, | Long JD, | Bockholt JH, | Paulsen JS, | Calhoun VD |Dynamic functional network connectivity in Huntington's disease and its associations with motor and cognitive measuresHum Brain Mapp1955-196840(6):20190415PMID:30618191DOI: 10.1002/hbm.24504Tang X, | Ross CA, | Johnson H, | Paulsen JS, | Younes L, | Albin RL, | Ratnanather JT, | Miller MI |Regional subcortical shape analysis in premanifest Huntington's diseaseHum Brain Mapp1419-143340(5):20190401PMID:30376191DOI: 10.1002/hbm.24456Toledo-Sherman L, | Breccia P, | Cachope R, | Bate JR, | Angulo-Herrera I, | Wishart G, | Matthews KL, | Martin SL, | Cox HC, | McAllister G, | Penrose SD, | Vater H, | Esmieu W, | Van de Poël A, | Van de Bospoort R, | Strijbosch A, | Lamers M, | Leonard P, | Jarvis RE, | Blackaby W, | Barnes K, | Eznarriaga M, | Dowler S, | Smith GD, | Fischer DF, | Lazari O, | Yates D, | Rose M, | Jang SW, | Muñoz-Sanjuan I, | Dominguez C |Optimization of potent and selective ataxia telangiectasia-mutated inhibitors suitable for a proof-of-concept study in Huntington's disease modelsJ Med Chem2988-300862(6):20190328PMID:30840447Reindl W, Baldo B, Schulz J, Janack I, Lindner I, Kleinschmidt M, | Sedaghat Y, | Thiede C, | Tillack K, | Schmidt C, | Cardaun I, | Schwagarus T, | Herrmann F, | Hotze M, | Osborne GF, | Herrmann S, | Weiss A, | Zerbinatti C, | Bates GP, | Bard J, | Munoz-Sanjuan I, | Macdonald D |Meso scale discovery-based assays for the detection of aggregated huntingtinPLoS Onee021352114(3):20190326PMID:30913220Murthy V, | Tebaldi T, | Yoshida T, | Erdin S, | Calzonetti T, | Vijayvargia R, | Tripathi T, | Kerschbamer E, | Seong IS, | Quattrone A, | Talkowski ME, | Gusella JF, | Georgopoulos K, | MacDonald ME, | Biagioli M |Hypomorphic mutation of the mouse Huntington's disease gene orthologuePLoS Genete100776515(3):20190321PMID:30897080Merienne N, | Meunier C, | Schneider A, | Seguin J, | Nair SS, | Rocher AB, | Le Gras S, | Keime C, | Faull R, | Pellerin L, | Chatton JY, | Neri C, | Merienne K, | Déglon N |Cell-type-specific gene expression profiling in adult mouse brain reveals normal and disease-state signaturesCell Rep2477-249326(9):20190226PMID:30811995Castaldo I, | De Rosa M, | Romano A, | Zuchegna C, | Squitieri F, | Mechelli R, | Peluso S, | Borrelli C, | Del Mondo A, | Salvatore E, | Vescovi LA, | Migliore S, | De Michele G, | Ristori G, | Romano S, | Avvedimento EV, | Porcellini A |DNA damage signatures in peripheral blood cells as biomarkers in prodromal huntington diseaseAnn Neurol296-30185(2):20190221PMID:30549309DOI: 10.1002/ana.25393Kang R, | Wang L, | Sanders SS, | Zuo K, | Hayden MR, | Raymond LA |Altered regulation of striatal neuronal N-Methyl-D-Aspartate receptor trafficking by palmitoylation in Huntington disease mouse modelFront Synaptic Neurosci11(3):20190221PMID:30846936PMCID: 6393405Goold R, | Flower M, | Moss DH, | Medway C, | Wood-Kaczmar A, | Andre R, | Farshim P, | Bates GP, | Holmans P, | Jones L, | Tabrizi SJ |FAN1 modifies Huntington's disease progression by stabilizing the expanded HTT CAG repeatHum Mol Genet650-66128(4):20190215PMID:30358836DOI: 10.1093/hmg/ddy375PMCID: 6360275Gatto RG, | Ye AQ, | Colon-Perez L, | Mareci TH, | Lysakowski A, | Price SD, | Brady ST, | Karaman M, | Morfini G, | Magin RL |Detection of axonal degeneration in a mouse model of Huntington's disease: comparison between diffusion tensor imaging and anomalous diffusion metricsMAGMA():20190215PMID:30771034Tousley A, | Iuliano M, | Weisman E, | Sapp E, | Richardson H, | Vodicka P, | Alexander J, | Aronin N, | DiFiglia M, | Kegel-Gleason KB |Huntingtin associates with the actin cytoskeleton and α-actinin isoforms to influence stimulus dependent morphology changesPLoS Onee021233714(2):20190215PMID:30768638Smatlikova P, | Juhas S, | Juhasova J, | Suchy T, | Hubalek Kalbacova M, | Ellederova Z, | Motlik J, | Klima J |Adipogenic differentiation of bone marrow-derived mesenchymal stem cells in pig transgenic model expressing human mutant huntingtinJ Huntingtons Dis33-518(1):20190213PMID:30584151DOI: 10.3233/JHD-180303Rieke L, | Fels M, | Schubert R, | Habbel B, | Matheis T, | Schuldenzucker V, | Kemper N, | Reilmann R |Activity behaviour of minipigs transgenic for the Huntington geneJ Huntingtons Dis23-318(1):20190213PMID:30689591DOI: 10.3233/JHD-180325Perez-Rosello T, | Gelman S, | Tombaugh G, | Cachope R, | Beaumont V, | Surmeier DJ |Enhanced striatopallidal gamma-aminobutyric acid (GABA)(A) receptor transmission in mouse models of huntington's diseaseMov Disord684-69634(5):20190206PMID:30726572DOI: 10.1002/mds.27622Ciarochi JA, | Johnson HJ, | Calhoun VD, | Liu J, | Espinoza FA, | Bockholt HJ, | Misiura M, | Caprihan A, | Plis S, | Paulsen JS, | Turner JA, | PREDICT-HD Investigators and Coordinators of the Huntington Study Group |Concurrent cross-sectional and longitudinal analyses of multivariate white matter profiles and clinical functioning in pre-diagnosis Huntington diseaseJ Huntingtons Dis199-2198(2):20190205PMID:30932891DOI: 10.3233/JHD-180332Padovan-Neto FE, | Jurkowski L, | Murray C, | Stutzmann GE, | Kwan M, | Ghavami A, | Beaumont V, | Park LC, | West AR |Age- and sex-related changes in cortical and striatal nitric oxide synthase in the Q175 mouse model of Huntington's diseaseNitric Oxide40-5083():20190201PMID:30528913Paulsen JS, | Lourens S, | Kieburtz K, | Zhang Y |Sample enrichment for clinical trials to show delay of onset in Huntington diseaseMov Disord274-28034(2):20190201PMID:30644132DOI: 10.1002/mds.27595Holley SM, | Galvan L, | Kamdjou T, | Cepeda C, | Levine MS |Striatal GABAergic interneuron dysfunction in the Q175 mouse model of Huntington's diseaseEur J Neurosci79-9349(1):20190130PMID:30472747DOI: 10.1111/ejn.14283Rodrigues FB, | Byrne LM, | De Vita E, | Johnson EB, | Hobbs NZ, | Thornton JS, | Scahill RI, | Wild EJ |Cerebrospinal fluid flow dynamics in Huntington's disease evaluated by phase contrast MRIEur J Neurosci1-8():20190128PMID:30687961DOI: 10.1111/ejn.14356Lu M, | Banetta L, | Young LJ, | Smith EJ, | Bates GP, | Zaccone A, | Kaminski Schierle GS, | Tunnacliffe A, | Kaminski CF |Live-cell super-resolution microscopy reveals a primary role for diffusion in polyglutamine-driven aggresome assemblyJ Biol Chem257-268294(1):20190104PMID:30401748PMCID: 6322900Osipovitch M, | Asenjo Martinez A, | Mariani JN, | Cornwell A, | Dhaliwal S, | Zou L, | Chandler-Militello D, | Wang S, | Li X, | Benraiss SJ, | Agate R, | Lampp A, | Benraiss A, | Windrem MS, | Goldman SA |Human ESC-derived chimeric mouse models of Huntington's disease reveal cell-intrinsic defects in glial progenitor cell differentiationCell Stem Cell107-12224(1):20190103PMID:30554964Luckhurst CA, | Aziz O, | Beaumont V, | Bürli RW, | Breccia P, | Maillard MC, | Haughan AF, | Lamers M, | Leonard P, | Matthews KL, | Raphy G, | Stott AJ, | Munoz-Sanjuan I, | Thomas B, | Wall M, | Wishart G, | Yates D, | Dominguez C |Development and characterization of a CNS-penetrant benzhydryl hydroxamic acid class IIa histone deacetylase inhibitorBioorg Med Chem Lett83-8829(1):20190101PMID:30463802
2018
AuthorsTitleJournal- Bravo-Arredondo JM, | Kegulian NC, | Schmidt T, | Pandey NK, | Situ AJ, | Ulmer TS, | Langen R |The folding equilibrium of huntingtin exon 1 monomer depends on its polyglutamine tractJ Biol Chem19613-19623293(51):20181221PMID:30315108PMCID: 6314148Naze S, | Humble J, | Zheng P, | Barton S, | Rangel-Barajas C, | Rebec GV, | Kozloski JR |Cortico-striatal cross-frequency coupling and gamma genesis disruptions in Huntington's disease mouse and computational modelseNeuro5(6):20181221PMID:30627632PMCID: 6325534Wang D, | Zhong L, | Li M, | Li J, | Tran K, | Ren L, | He R, | Xie J, | Moser RP, | Fraser C, | Kuchel T, | Sena-Esteves M, | Flotte TR, | Aronin N, | Gao G |Adeno-associated virus neutralizing antibodies in large animals and their impact on brain intraparenchymal gene transferMol Ther Methods Clin Dev65-7211():20181214PMID:30397628PMCID: 6205343McBride SD, | Morton AJ |Indices of comparative cognition: assessing animal models of human brain functionExp Brain Res3379-3390236(12):20181203PMID:30267138PMCID: 6267686Kuljis D, | Kudo T, | Tahara Y, | Ghiani CA, | Colwell CS |Pathophysiology in the suprachiasmatic nucleus in mouse models of Huntington's diseaseJ Neurosci Res1862-187596(12):20181203PMID:30168855DOI: 10.1002/jnr.24320Mondo E, | Moser R, | Gao G, | Mueller C, | Sena-Esteves M, | Sapp E, | Pfister E, | O'Connell D, | Takle K, | Erger KE, | Liu W, | Conlon TJ, | DiFiglia M, | Gounis MJ, | Aronin N |Selective neuronal uptake and distribution of AAVrh8, AAV9, and AAVrh10 in sheep after intra-striatal administrationJ Huntingtons Dis309-3197(4):20181124PMID:30320596DOI: 10.3233/JHD-180302Garcia TP, | Wang Y, | Shoulson I, | Paulsen JS, | Marder K |Disease progression in Huntington disease: an analysis of multiple longitudinal outcomesJ Huntingtons Dis337-3447(4):20181123PMID:30400103DOI: 10.3233/JHD-180297Long JD, | Mills JA |Joint modeling of multivariate longitudinal data and survival data in several observational studies of Huntington's diseaseBMC Med Res Methodol13818(1):20181116PMID:30445915PMCID: 6240282Godinho BMDC, | Henninger N, | Bouley J, | Alterman JF, | Haraszti RA, | Gilbert JW, | Sapp E, | Coles AH, | Biscans A, | Nikan M, | Echeverria D, | DiFiglia M, | Aronin N, | Khvorova A |Transvascular delivery of hydrophobically modified siRNAs: gene silencing in the rat brain upon disruption of the blood-brain barrierMol Ther2580-259126(11):20181107PMID:30143435Rocha NP, | Mwangi B, | Gutierrez Candano CA, | Sampaio C, | Furr Stimming E, | Teixeira AL |The clinical picture of psychosis in manifest Huntington's disease: a comprehensive analysis of the Enroll-HD databaseFront Neurol9(930):20181106PMID:30459704PMCID: 6232301Rowley CD, | Tabrizi SJ, | Scahill RI, | Leavitt BR, | Roos RAC, | Durr A, | Bock NA |Altered intracortical T(1)-weighted/T(2)-weighted ratio signal in Huntington's diseaseFront Neurosci80512():20181105PMID:30455625PMCID: 6230564Zhang J, | Gregory S, | Scahill RI, | Durr A, | Thomas DL, | Lehericy S, | Rees G, | Tabrizi SJ, | Zhang H, | TrackOn-HD investigators |In vivo characterization of white matter pathology in premanifest huntington's diseaseAnn Neurol497-50484(4):20181029PMID:30063250DOI: 10.1002/ana.25309PMCID: 6221120Bertoglio D, | Verhaeghe J, | Kosten L, | Thomae D, | Van der Linden A, | Stroobants S, | Wityak J, | Dominguez C, | Mrzljak L, | Staelens S |MR-based spatial normalization improves [18F]MNI-659 PET regional quantification and detectability of disease effect in the Q175 mouse model of Huntington's diseasePLoS Onee020661313(10):20181026PMID:30365550PMCID: 6203386Piiponniemi TO, | Parkkari T, | Heikkinen T, | Puoliväli J, | Park LC, | Cachope R, | Kopanitsa MV |Impaired performance of the Q175 mouse model of Huntington's disease in the touch screen paired associates learning taskFront Behav Neurosci12(226):20181002PMID:30333735PMCID: 6176131Aron R, | Pellegrini P, | Green EW, | Maddison DC, | Opoku-Nsiah K, | Wong JS, | Daub AC, | Giorgini F, | Finkbeiner S |Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's diseaseNat Commun31919(1):20180928PMID:30266909PMCID: 6162324Neueder A, | Dumas AA, | Benjamin AC, | Bates GP |Regulatory mechanisms of incomplete huntingtin mRNA splicingNat Commun39559(1):20180927PMID:30262848PMCID: 6160442Byrne LM, | Rodrigues FB, | Johnson EB, | Wijeratne PA, | De Vita E, | Alexander DC, | Palermo G, | Czech C, | Schobel S, | Scahill RI, | Heslegrave A, | Zetterberg H, | Wild EJ |Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington's diseaseSci Transl Medeaat710810(458):20180912PMID:30209243Siebzehnrübl FA, | Raber KA, | Urbach YK, | Schulze-Krebs A, | Canneva F, | Moceri S, | Habermeyer J, | Achoui D, | Gupta B, | Steindler DA, | Stephan M, | Nguyen HP, | Bonin M, | Riess O, | Bauer A, | Aigner L, | Couillard-Despres S, | Paucar MA, | Svenningsson P, | Osmand A, | Andreew A, | Zabel C, | Weiss A, | Kuhn R, | Moussaoui S, | Blockx I, | Van der Linden A, | Cheong RY, | Roybon L, | Petersén Å, | von Hörsten S |Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibitionProc Natl Acad Sci USAE8765-E8774115(37):20180911PMID:30150378PMCID: 6140493Ast A, | Buntru A, | Schindler F, | Hasenkopf R, | Schulz A, | Brusendorf L, | Klockmeier K, | Grelle G, | McMahon B, | Niederlechner H, | Jansen I, | Diez L, | Edel J, | Boeddrich A, | Franklin SA, | Baldo B, | Schnoegl S, | Kunz S, | Purfürst B, | Gaertner A, | Kampinga HH, | Morton AJ, | Petersén Å, | Kirstein J, | Bates GP, | Wanker EE |mHTT seeding activity: a marker of disease progression and neurotoxicity in models of Huntington's diseaseMol Cell675-68871(5):20180906PMID:30193095Evers MM, | Miniarikova J, | Juhas S, | Vallès A, | Bohuslavova B, | Juhasova J, | Skalnikova HK, | Vodicka P, | Valekova I, | Brouwers C, | Blits B, | Lubelski J, | Kovarova H, | Ellederova Z, | van Deventer SJ, | Petry H, | Motlik J, | Konstantinova P |AAV5-miHTT gene therapy demonstrates broad distribution and strong human mutant huntingtin lowering in a Huntington's disease minipig modelMol Ther2163-217726(9):20180905PMID:30007561PMCID: 6127509Didiot MC, | Ferguson CM, | Ly S, | Coles AH, | Smith AO, | Bicknell AA, | Hall LM, | Sapp E, | Echeverria D, | Pai AA, | DiFiglia M, | Moore MJ, | Hayward LJ, | Aronin N, | Khvorova A |Nuclear localization of Huntingtin mRNA is specific to cells of neuronal originCell Rep2553-256024(10):20180904PMID:30184490Goodliffe JW, | Song H, | Rubakovic A, | Chang W, | Medalla M, | Weaver CM, | Luebke JI |Differential changes to D1 and D2 medium spiny neurons in the 12-month-old Q175+/- mouse model of Huntington's diseasePLoS Onee020062613(8):20180817PMID:30118496PMCID: 6097649Haraszti RA, | Miller R, | Didiot MC, | Biscans A, | Alterman JF, | Hassler MR, | Roux L, | Echeverria D, | Sapp E, | DiFiglia M, | Aronin N, | Khvorova A |Optimized cholesterol-siRNA chemistry improves productive loading onto extracellular vesiclesMol Ther1973-198226(8):20180801PMID:29937418Pido-Lopez J, | Andre R, | Benjamin AC, | Ali N, | Farag S, | Tabrizi SJ, | Bates GP |In vivo neutralization of the protagonist role of macrophages during the chronic inflammatory stage of Huntington's diseaseSci Rep114478(1):20180730PMID:30061661Mir A, | Alterman JF, | Hassler MR, | Debacker AJ, | Hudgens E, | Echeverria D, | Brodsky MH, | Khvorova A, | Watts JK, | Sontheimer EJ |Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editingNat Commun26419(1):20180706PMID:29980686Ko J, | Isas JM, | Sabbaugh A, | Yoo JH, | Pandey NK, | Chongtham A, | Ladinsky M, | Wu WL, | Rohweder H, | Weiss A, | Macdonald D, | Munoz-Sanjuan I, | Langen R, | Patterson PH, | Khoshnan A |Identification of distinct conformations associated with monomers and fibril assemblies of mutant huntingtinHum Mol Genet2330–234327(13):20180701PMID:29912367DOI: 10.1093/hmg/ddy141Verhaeghe J, | Bertoglio D, | Kosten L, | Thomae D, | Verhoye M, | Van Der Linden A, | Wyffels L, | Stroobants S, | Wityak J, | Dominguez C, | Mrzljak L, | Staelens S |Noninvasive relative quantification of [(11)C]ABP688 PET imaging in mice versus an input function measured over an arteriovenous shuntFront Neurol9(516):20180629PMID:30013509PMCID: 6036254Reif A, | Chiki A, | Ricci J, | Lashuel HA |Generation of native, untagged Huntingtin Exon1 monomer and fibrils using a SUMO fusion strategyJ Vis Exp136():20180627PMID:30010666DOI: 10.3791/57506Biscans A, | Haraszti RA, | Echeverria D, | Miller R, | Didiot MC, | Nikan M, | Roux L, | Aronin N, | Khvorova A |Hydrophobicity of lipid-conjugated siRNAs predicts productive loading to small extracellular vesiclesMol Ther1520-152826(6):20180606PMID:29699940Shin B, | Jung R, | Oh H, | Owens GE, | Lee H, | Kwak S, | Lee R, | Cotman SL, | Lee JM, | MacDonald ME, | Song JJ, | Vijayvargia R, | Seong IS |Novel DNA aptamers that bind to mutant Huntingtin and modify its activityMol Ther Nucleic Acids416-42811():20180601PMID:29858077PMCID: 5992459Covey DP, | Dantrassy HM, | Yohn SE, | Castro A, | Conn PJ, | Mateo Y, | Cheer JF |Inhibition of endocannabinoid degradation rectifies motivational and dopaminergic deficits in the Q175 mouse model of Huntington's diseaseNeuropsychopharmacology2056–206343():20180601PMID:29925886PMCID: 6098121Suelves N, | Miguez A, | López-Benito S, | Barriga GG, | Giralt A, | Alvarez-Periel E, | Arévalo JC, | Alberch J, | Ginés S, | Brito V |Early downregulation of p75(NTR) by genetic and pharmacological approaches delays the onset of motor deficits and striatal dysfunction in Huntington's disease miceMol Neurobiol():20180528PMID:29804232Martin DDO, | Kay C, | Collins JA, | Nguyen YT, | Slama RA, | Hayden MR |A human huntingtin SNP alters post-translational modification and pathogenic proteolysis of the protein causing Huntington diseaseSci Rep80969(1):20180525PMID:29802276Bertoglio D, | Kosten L, | Verhaeghe J, | Thomae D, | Wyffels L, | Stroobants S, | Wityak J, | Dominguez C, | Mrzljak L, | Staelens S |Longitudinal characterization of mGluR5 using (11)C-ABP688 PET imaging in the Q175 mouse model of Huntington's diseaseJ Nucl Med1723-172759(11):20180524PMID:29794227McClory H, | Wang X, | Sapp E, | Gatune LW, | Iuliano M, | Wu CY, | Nathwani G, | Kegel-Gleason KB, | DiFiglia M, | Li X |The COOH-terminal domain of huntingtin interacts with RhoGEF kalirin and modulates cell survivalSci Rep8(1):20180522PMID:29789657Schuldenzucker V, | Schubert R, | Muratori LM, | Freisfeld F, | Rieke L, | Matheis T, | Schramke S, | Motlik J, | Kemper N, | Radespiel U, | Reilmann R |Behavioral assessment of stress compensation in minipigs transgenic for the Huntington gene using cortisol levels: a proof-of-concept studyJ Huntingtons Dis151-1617(2):20180519PMID:29843247DOI: 10.3233/JHD-180285Gregory S, | Long JD, | Klöppel S, | Razi A, | Scheller E, | Minkova L, | Johnson EB, | Durr A, | Roos RAC, | Leavitt BR, | Mills JA, | Stout JC, | Scahill RI, | Tabrizi SJ, | Rees G, | Track-On investigators |Testing a longitudinal compensation model in premanifest Huntington's diseaseBrain():20180518PMID:29788038DOI: 10.1093/brain/awy122Chao MJ, | Kim KH, | Shin JW, | Lucente D, | Wheeler VC, | Li H, | Roach JC, | Hood L, | Wexler NS, | Jardim LB, | Holmans P, | Jones L, | Orth M, | Kwak S, | MacDonald ME, | Gusella JF, | Lee JM |Population-specific genetic modification of Huntington's disease in VenezuelaPLoS Genete100727414(5):20180511PMID:29750799Mestre TA, | Busse M, | Davis AM, | Quinn L, | Rodrigues FB, | Burgunder JM, | Carlozzi NE, | Walker F, | Ho AK, | Sampaio C, | Goetz CG, | Cubo E, | Martinez-Martin P, | Stebbins GT, | Members of the MDS Committee on Rating Scales Development |Rating scales and performance-based measures for assessment of functional ability in Huntington's disease: critique and recommendationsMov Disord Clin Pract361-3725(4):20180509PMID:30363510DOI: 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