CHDI
Listed here are over 1,075 publications that describe some of the research funded (in whole or in part) by CHDI Foundation. You can also view just the subset of publications that have CHDI staff as authors.
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Title
Journal
Downing NR, Kim JI, Williams JK, Long JD, Mills JA, Paulsen JS, Predict-Hd Investigators, Coordinators of the Huntington Study Group
WHODAS 2.0 in prodromal Huntington disease: measures of functioning in neuropsychiatric disease
Dominguez C, Munoz-Sanjuan I
Foundation-directed therapeutic development in Huntington`s disease
McKinstry SU, Karadeniz YB, Worthington AK, Hayrapetyan VY, Ozlu MI, Serafin-Molina K, Risher WC, Ustunkaya T, Dragatsis I, Zeitlin S, Yin HH, Eroglu C
Huntingtin is required for normal excitatory synapse development in cortical and striatal circuits
Plotkin JL, Day M, Peterson JD, Xie Z, Kress GJ, Rafalovich I, Kondapalli J, Gertler TS, Flajolet M, Greengard P, Stavarache M, Kaplitt MG, Rosinski J, Chan CS, Surmeier DJ
Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington`s disease
Morton AJ, Rudiger SR, Wood NI, Sawiak SJ, Brown GC, Mclaughlan CJ, Kuchel TR, Snell RG, Faull RL, Bawden CS
Early and progressive circadian abnormalities in Huntington's disease sheep are unmasked by social environment
Andre R, Scahill RI, Haider S, Tabrizi SJ
Biomarker development for Huntington's disease
Sepers MD, Raymond LA
Mechanisms of synaptic dysfunction and excitotoxicity in Huntington`s disease
Signer, E
Through postdoc eyes
Georgiou-Karistianis N, Stout JC, Domínguez D JF, Carron SP, Ando A, Churchyard A, Chua P, Bohanna I, Dymowski AR, Poudel G, Egan GF
Functional magnetic resonance imaging of working memory in Huntington's disease: cross-sectional data from the IMAGE-HD study
Paul BD, Sbodio JI, Xu R, Vandiver MS, Cha JY, Snowman AM, Snyder SH
Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease
Poudel GR, Stout JC, Domínguez D JF, Salmon L, Churchyard A, Chua P, Georgiou-Karistianis N, Egan GF
White matter connectivity reflects clinical and cognitive status in Huntington's disease
Tong X, Ao Y, Faas GC, Nwaobi SE, Xu J, Haustein MD, Anderson MA, Mody I, Olsen ML, Sofroniew MV, Khakh BS
Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice
Wang N, Gray M, Lu XH, Cantle JP, Holley SM, Greiner E, Gu X, Shirasaki D, Cepeda C, Li Y, Dong H, Levine MS, Yang XW
Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease
Yu A, Shibata Y, Shah B, Calamini B, Lo DC, Morimoto RI
Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition
An MC, O’Brien RN, Zhang N, Patra BN, De La Cruz M, Ray A, Ellerby LM
Polyglutamine disease modeling: epitope based screen for homologous recombination using CRISPR/Cas9 system
Kolodziejczyk K, Parsons MP, Southwell AL, Hayden MR, Raymond LA
Striatal synaptic dysfunction and hippocampal plasticity deficits in the Hu97/18 mouse model of Huntington disease
Matsui JT, Vaidya JG, Johnson HJ, Magnotta VA, Long JD, Mills JA, Lowe MJ, Sakaie KE, Rao SM, Smith MM, Paulsen JS
Diffusion weighted imaging of prefrontal cortex in prodromal Huntington's disease
Zeef DH, Jahanshahi A, Vlamings R, Casaca-Carreira J, Santegoeds RG, Janssen ML, Oosterloo M, Temel Y
An experimental model for Huntington's chorea?
Crotti A, Benner C, Kerman BE, Gosselin D, Lagier-Tourenne C, Zuccato C, Cattaneo E, Gage FH, Cleveland DW, Glass CK
Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors
Skodda S, Schlegel U, Hoffmann R, Saft C
Impaired motor speech performance in Huntington's disease
J Neural Transm (Vienna)
April 1, 2014
121 (4) :399-407
121 (4) :399-407
PMID: 24221215
Jones R, Stout JC, Labuschagne I, Say M, Justo D, Coleman A, Dumas EM, Hart E, Owen G, Durr A, Leavitt BR, Roos R, O’Regan A, Langbehn D, Tabrizi SJ, Frost C
The potential of composite cognitive scores for tracking progression in Huntington's disease
Jiang H, Sun YM, Hao Y, Yan YP, Chen K, Xin SH, Tang YP, Li XH, Jun T, Chen YY, Liu ZJ, Wang CR, Li H, Pei Z, Shang HF, Zhang BR, Gu WH, Wu ZY, Tang BS, Burgunder JM, Chinese HD Network
Huntingtin gene CAG repeat numbers in Chinese patients with Huntington's disease and controls
Ross CA, Aylward EH, Wild EJ, Langbehn DR, Long JD, Warner JH, Scahill RI, Leavitt BR, Stout JC, Paulsen JS, Reilmann R, Unschuld PG, Wexler A, Margolis RL, Tabrizi SJ
Huntington disease: natural history, biomarkers and prospects for therapeutics
Cuesta M, Aungier J, Morton AJ
Behavioral therapy reverses circadian deficits in a transgenic mouse model of Huntington's disease
Cole JH, Farmer RE, Rees EM, Johnson HJ, Frost C, Scahill RI, Hobbs NZ
Test-retest reliability of diffusion tensor imaging in Huntington's disease
Tourette C, Li B, Bell R, O’Hare S, Kaltenbach LS, Mooney SD, Hughes RE
A large scale Huntingtin protein interaction network implicates Rho GTPase signaling pathways in Huntington disease
Long JD, Paulsen JS, Marder K, Zhang Y, Kim JI, Mills JA, Researchers of the PREDICT-HD Huntington’s Study Group
Tracking motor impairments in the progression of Huntington's disease
Hart EP, Dumas EM, Schoonderbeek A, Wolthuis SC, van Zwet EW, Roos RA
Motor dysfunction influence on executive functioning in manifest and premanifest Huntington's disease
Novak MJ, Seunarine KK, Gibbard CR, Hobbs NZ, Scahill RI, Clark CA, Tabrizi SJ
White matter integrity in premanifest and early Huntington's disease is related to caudate loss and disease progression
Padowski JM, Weaver KE, Richards TL, Laurino MY, Samii A, Aylward EH, Conley KE
Neurochemical correlates of caudate atrophy in Huntington's disease
Träger U, Andre R, Lahiri N, Magnusson-Lind A, Weiss A, Grueninger S, McKinnon C, Sirinathsinghji E, Kahlon S, Pfister EL, Moser R, Hummerich H, Antoniou M, Bates GP, Luthi-Carter R, Lowdell MW, Björkqvist M, Ostroff GR, Aronin N, Tabrizi SJ
HTT-lowering reverses Huntington's disease immune dysfunction caused by NFκB pathway dysregulation
Poudel GR, Egan GF, Churchyard A, Chua P, Stout JC, Georgiou-Karistianis N
Abnormal synchrony of resting state networks in premanifest and symptomatic Huntington disease: the IMAGE-HD study
J Psychiatry Neurosci
March 1, 2014
39 (2) :87-96
39 (2) :87-96
PMID: 24083458
PMCID: 3937285
DOI: 10.1503/jpn.120226
Younes L, Ratnanather JT, Brown T, Aylward E, Nopoulos P, Johnson H, Magnotta VA, Paulsen JS, Margolis RL, Albin RL, Miller MI, Ross CA, PREDICT-HD Investigators and Coordinators of the HSG
Regionally selective atrophy of subcortical structures in prodromal HD as revealed by statistical shape analysis
Beglinger LJ, Adams WH, Langbehn D, Fiedorowicz JG, Jorge R, Biglan K, Caviness J, Olson B, Robinson RG, Kieburtz K, Paulsen JS
Results of the citalopram to enhance cognition in Huntington disease trial
Sanders SS, Mui KK, Sutton LM, Hayden MR
Identification of binding sites in huntingtin for the huntingtin interacting proteins HIP14 and HIP14L
Mealer RG, Murray AJ, Shahani N, Subramaniam S, Snyder SH
Rhes, a striatal-selective protein implicated in Huntington disease, binds beclin-1 and activates autophagy
Sajjad MU, Green EW, Miller-Fleming L, Hands S, Herrera F, Campesan S, Khoshnan A, Outeiro TF, Giorgini F, Wyttenbach A
DJ-1 modulates aggregation and pathogenesis in models of Huntington's disease
Bard J, Wall MD, Lazari O, Arjomand J, Munoz-Sanjuan I
Advances in huntington disease drug discovery: novel approaches to model disease phenotypes
Dodel R, Jonsson B, Reese JP, Winter Y, Martinez-Martin P, Holloway R, Sampaio C, Ruzicka E, Hawthorne G, Oertel W, Poewe W, Stebbins G, Rascol O, Goetz CG, Schrag A
Measurement of costs and scales for outcome evaluation in health economic studies of Parkinson`s disease
Buonincontri G, Wood NI, Puttick SG, Ward AO, Carpenter TA, Sawiak SJ, Morton AJ
Right ventricular dysfunction in the R6/2 transgenic mouse model of Huntington's disease is unmasked by dobutamine
J Huntingtons Dis
January 31, 2014
3 (1) :25-32
3 (1) :25-32
PMID: 24744818
PMCID: 3986496
DOI: 10.3233/JHD-130083