CHDI
Listed here are over 975 publications that describe some of the research funded (in whole or in part) by CHDI Foundation. You can also view just the subset of publications that have CHDI staff as authors.
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Title
Journal
Mrzljak L, Munoz-Sanjuan I
Therapeutic strategies for Huntington`s Disease
Poudel GR, Stout JC, Dominguez DJ, Gray MA, Salmon L, Churchyard A, Chua P, Borowsky B, Egan GF, Georgiou-Karistianis N
Functional changes during working memory in Huntington`s disease: 30-month longitudinal data from the IMAGE-HD study
Lu XH, Mattis VB, Wang N, Al-Ramahi I, van den Berg N, Fratantoni SA, Waldvogel H, Greiner E, Osmand A, Elzein K, Xiao J, Dijkstra S, de Pril R, Vinters HV, Faull R, Signer E, Kwak S, Marugan JJ, Botas J, Fischer DF, Svendsen CN, Munoz-Sanjuan I, Yang XW
Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease
Fodale V, Kegulian NC, Verani M, Cariulo C, Azzollini L, Petricca L, Daldin M, Boggio R, Padova A, Kuhn R, Pacifici R, Macdonald D, Schoenfeld RC, Park H, Isas JM, Langen R, Weiss A, Caricasole A
Polyglutamine- and temperature-dependent conformational rigidity in mutant huntingtin revealed by immunoassays and circular dichroism spectroscopy
Paulsen JS, Long JD, Ross CA, Harrington DL, Erwin CJ, Williams JK, Westervelt HJ, Johnson HJ, Aylward EH, Zhang Y, Bockholt HJ, Barker RA, Predict-Hd Investigators, Coordinators of the Huntington Study Group
Prediction of manifest Huntington`s disease with clinical and imaging measures: a prospective observational study
Ochaba J, Lukacsovich T, Csikos G, Zheng S, Margulis J, Salazar L, Mao K, Lau AL, Yeung SY, Humbert S, Saudou F, Klionsky DJ, Finkbeiner S, Zeitlin SO, Marsh JL, Housman DE, Thompson LM, Steffan JS
Potential function for the Huntingtin protein as a scaffold for selective autophagy
Rees EM, Farmer R, Cole JH, Haider S, Durr A, Landwehrmeyer B, Scahill RI, Tabrizi SJ, Hobbs NZ
Cerebellar abnormalities in Huntington's disease: a role in motor and psychiatric impairment?
van Wamelen DJ, Aziz NA, Roos RA, Swaab DF
Hypothalamic alterations in Huntington's disease patients: comparison with genetic rodent models
Rees EM, Farmer R, Cole JH, Henley SM, Sprengelmeyer R, Frost C, Scahill RI, Hobbs NZ, Tabrizi SJ
Inconsistent emotion recognition deficits across stimulus modalities in Huntington׳s disease
Neuropsychologia
November 1, 2014
64 :99-104
64 :99-104
PMID: 25250707
Yao J, Ong SE, Bajjalieh S
Huntingtin is associated with cytomatrix proteins at the presynaptic terminal
Deng YP, Wong T, Wan JY, Reiner A
Differential loss of thalamostriatal and corticostriatal input to striatal projection neuron types prior to overt motor symptoms in the Q140 knock-in mouse model of Huntington's disease
Kalliolia E, Silajdžić E, Nambron R, Hill NR, Doshi A, Frost C, Watt H, Hindmarsh P, Björkqvist M, Warner TT
Plasma melatonin is reduced in Huntington's disease
Brito V, Giralt A, Enriquez-Barreto L, Puigdellívol M, Suelves N, Zamora-Moratalla A, Ballesteros JJ, Martín ED, Dominguez-Iturza N, Morales M, Alberch J, Ginés S
Neurotrophin receptor p75(NTR) mediates Huntington's disease-associated synaptic and memory dysfunction
Wild EJ, Tabrizi SJ
Targets for future clinical trials in Huntington's disease: what's in the pipeline?
Sampaio C, Borowsky B, Reilmann R
Clinical trials in Huntington`s disease: Interventions in early clinical development and newer methodological approaches
Howland DS, Munoz-Sanjuan I
Mind the gap: models in multiple species needed for therapeutic development in Huntington`s disease
Stout JC, Queller S, Baker KN, Cowlishaw S, Sampaio C, Fitzer-Attas C, Borowsky B, HD-Cab Investigators
HD-CAB: a cognitive assessment battery for clinical trials in Huntington`s disease 1,2,3
Munafo M, Noble S, Browne WJ, Brunner D, Button K, Ferreira J, Holmans P, Langbehn D, Lewis G, Lindquist M, Tilling K, Wagenmakers EJ, Blumenstein R
Scientific rigor and the art of motorcycle maintenance
Smith GA, Rocha EM, McLean JR, Hayes MA, Izen SC, Isacson O, Hallett PJ
Progressive axonal transport and synaptic protein changes correlate with behavioral and neuropathological abnormalities in the heterozygous Q175 KI mouse model of Huntington`s disease
Kozak R, Campbell BM, Strick CA, Horner W, Hoffmann WE, Kiss T, Chapin DS, McGinnis D, Abbott AL, Roberts BM, Fonseca K, Guanowsky V, Young DA, Seymour PA, Dounay A, Hajos M, Williams GV, Castner SA
Reduction of brain kynurenic acid improves cognitive function
Georgiou-Karistianis N, Long JD, Lourens SG, Stout JC, Mills JA, Paulsen JS, Predict-Hd Investigators and Coordinators Of The Huntington Study Group
Movement sequencing in Huntington disease
Butland SL, Sanders SS, Schmidt ME, Riechers SP, Lin DT, Martin DD, Vaid K, Graham RK, Singaraja RR, Wanker EE, Conibear E, Hayden MR
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease
Mielcarek M, Inuabasi L, Bondulich MK, Muller T, Osborne GF, Franklin SA, Smith DL, Neueder A, Rosinski J, Rattray I, Protti A, Bates GP
Dysfunction of the CNS-heart axis in mouse models of Huntington`s disease
Downing NR, Kim JI, Williams JK, Long JD, Mills JA, Paulsen JS, Predict-Hd Investigators, Coordinators of the Huntington Study Group
WHODAS 2.0 in prodromal Huntington disease: measures of functioning in neuropsychiatric disease
Dominguez C, Munoz-Sanjuan I
Foundation-directed therapeutic development in Huntington`s disease
McKinstry SU, Karadeniz YB, Worthington AK, Hayrapetyan VY, Ozlu MI, Serafin-Molina K, Risher WC, Ustunkaya T, Dragatsis I, Zeitlin S, Yin HH, Eroglu C
Huntingtin is required for normal excitatory synapse development in cortical and striatal circuits
Plotkin JL, Day M, Peterson JD, Xie Z, Kress GJ, Rafalovich I, Kondapalli J, Gertler TS, Flajolet M, Greengard P, Stavarache M, Kaplitt MG, Rosinski J, Chan CS, Surmeier DJ
Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington`s disease
Morton AJ, Rudiger SR, Wood NI, Sawiak SJ, Brown GC, Mclaughlan CJ, Kuchel TR, Snell RG, Faull RL, Bawden CS
Early and progressive circadian abnormalities in Huntington's disease sheep are unmasked by social environment
Andre R, Scahill RI, Haider S, Tabrizi SJ
Biomarker development for Huntington's disease
Sepers MD, Raymond LA
Mechanisms of synaptic dysfunction and excitotoxicity in Huntington`s disease
Signer, E
Through postdoc eyes
Georgiou-Karistianis N, Stout JC, Domínguez D JF, Carron SP, Ando A, Churchyard A, Chua P, Bohanna I, Dymowski AR, Poudel G, Egan GF
Functional magnetic resonance imaging of working memory in Huntington's disease: cross-sectional data from the IMAGE-HD study
Paul BD, Sbodio JI, Xu R, Vandiver MS, Cha JY, Snowman AM, Snyder SH
Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease
Poudel GR, Stout JC, Domínguez D JF, Salmon L, Churchyard A, Chua P, Georgiou-Karistianis N, Egan GF
White matter connectivity reflects clinical and cognitive status in Huntington's disease
Tong X, Ao Y, Faas GC, Nwaobi SE, Xu J, Haustein MD, Anderson MA, Mody I, Olsen ML, Sofroniew MV, Khakh BS
Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice
Wang N, Gray M, Lu XH, Cantle JP, Holley SM, Greiner E, Gu X, Shirasaki D, Cepeda C, Li Y, Dong H, Levine MS, Yang XW
Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease
Yu A, Shibata Y, Shah B, Calamini B, Lo DC, Morimoto RI
Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition
An MC, O’Brien RN, Zhang N, Patra BN, De La Cruz M, Ray A, Ellerby LM
Polyglutamine disease modeling: epitope based screen for homologous recombination using CRISPR/Cas9 system
Kolodziejczyk K, Parsons MP, Southwell AL, Hayden MR, Raymond LA
Striatal synaptic dysfunction and hippocampal plasticity deficits in the Hu97/18 mouse model of Huntington disease
Matsui JT, Vaidya JG, Johnson HJ, Magnotta VA, Long JD, Mills JA, Lowe MJ, Sakaie KE, Rao SM, Smith MM, Paulsen JS
Diffusion weighted imaging of prefrontal cortex in prodromal Huntington's disease