Platform Lead, Compound Mangement & Cheminformatics

CHDI Management:  Job Opening


Title: Platform Lead Compound Management and Cheminformatics

Type of employment: full-time

Location: Los Angeles, CA or Princeton, NJ / currently hybrid

Other:  Vaccination against COVID-19 is a prerequisite for employment at CHDI Management



CHDI Foundation, Inc. is a privately-funded, not-for-profit, biomedical research organization that is exclusively dedicated to rapidly discovering and developing therapies that slow the progression of Huntington’s disease (HD). Our scientists work closely with a network of more than 600 researchers in academic and industrial laboratories around the world in the pursuit of these novel therapies, providing strategic scientific direction to ensure that our common goals remain in focus. This helps bridge the translational gap that often exists between academic and industrial research pursuits and that adds costly delays to therapy development. In its role as a collaborative enabler, CHDI seeks to bring the right partners together to identify and address critical scientific issues and move drug candidates to clinical evaluation as rapidly as possible. Our activities extend from exploratory biology to the identification and validation of therapeutic targets, and from drug discovery and development to clinical studies and trials.


CHDI has a position open for an individual with compound management and cheminformatics experience. The individual will be based in either Princeton, NJ or Los Angeles, CA.


Job responsibilities:


Responsibilities of this position include:

  • Compound registration, compound dispatching, compound property profiling and filtering, uploading of chemical data.
  • Curation of the company’s internal chemistry and assay databases.
  • Working with information scientists, computational chemists, medicinal chemists, protein crystallographers, and biologists to advance projects in Research Informatics.
  • Participation in the maintenance and extension of cheminformatics applications such as Dotmatics Browser, Vortex, Biovia Pipeline Pilot, and inhouse developed applications.


Job requirements:

  • Minimum B.S. degree, preferred M.S. or Ph.D. degree in chemistry or a related field.
  • Hands-on experience in cheminformatics and compound management in the pharmaceutical industry.
  • Experience with data analysis methods and applications (Dotmatics, Certara D360 and equivalent).
  • Experience with configuration of software such as Dotmatics applications or Pipeline Pilot.
  • Experience with software development using specialized or general-purpose programming languages (Python, Java, Pipeline Pilot)
  • Experience with data architecture design, databases (RDBMS and others), and SQL.
  • Experience in business systems analysis.
  • Ability to work in cross-functional teams of computational chemists, medicinal chemists, protein crystallographers, biologists, and IT staff.
  • Experience in managing IT projects.
  • Experience leading teams of external consultants.
  • Self-motivator, resourceful, able to work independently.
  • Strong organizational and multitasking skills.
  • Superior written and oral communication skills.



Salary Range $80,000-120,000. Exact compensation will vary based on experience.

Please send resumes to