Director, Clinical Statistics

Job Title

Director, Clinical Statistics

Job Location

The position will be based in Princeton, NJ (currently hybrid)

Job Reports To

Medical Vice President, Clinical Research

Other

Vaccination against COVID-19 is a prerequisite for employment at CHDI Management.

Job Description

CHDI is a privately-funded, not-for-profit biomedical research organization devoted to a single disease – Huntington’s disease. Our mission is to develop drugs that will slow the progression of Huntington’s disease (HD) and provide meaningful clinical benefit to patients. CHDI is a “science first” organization; our foremost consideration is to do the best science as quickly and efficiently as possible.

CHDI’s Clinical Team oversees a portfolio of projects aimed at understanding the natural progression of HD disease, developing the best biomarkers and outcome measures for use in clinical trials, finding ways to expedite and improve the execution of clinical trials, paving relevant regulatory pathways, and working with external partners to support their clinical development plans. The team engages a diverse array of partners to help manage this portfolio, including academic institutions, government agencies, contract research organizations (CROs), biotech and pharmaceutical companies.

Job responsibilities

• Manage a portfolio of internal and external statistical modeling collaborations in support of CHDI’s clinical development efforts.
• Contribute to ongoing scientific dialog around the planning and execution of statistical and modeling efforts within the Foundation.
• Provide statistical help for internal CHDI protocols.
• Clean, manage and analyze data and communicate results as needed.

Professional qualifications/skills

The ideal candidate will:

• Have an advanced degree (Phd) in biostatistics/ bioinformatics/ data science or in biology/ neuroscience/ molecular genetics or related fields with adequate background in biostatistics and epidemiology. Prior experience or strong interest in healthcare or biological research preferred; 2-5 years of work experience.
• Demonstrate the ability to
  • Apply experimental design concepts to the planning of disease progression modeling using conventional and innovative research methods.
  • Code and analyze data in a one or more standard programming/scripting languages (e.g.  R, MATLAB, NONMEM, STATA, SAS, Python, Perl, Stan).
  • Learn new statistical/data mining techniques and programming languages as needed.
  • Interpret methodological results and convey them to a non-technical audience in an easy and effective manner.
  • Manage and clean data.

Personal skills

• Demonstrated skill in prioritization and time management.
• Demonstrated ability to organize, initiate and work independently to address responsibilities.
• Team oriented with excellent interpersonal skills.
• Excellent oral and written communication skills.

About CHDI Foundation, Inc.

CHDI is a private, not-for-profit research organization. We work with an international network of scientists to discover drugs that slow the progression of Huntington’s disease (HD) and provide meaningful clinical benefit to patients. We seek to accelerate scientific progress by serving as a collaborative enabler. We encourage and support cooperation and collaboration among HD researchers. Our strategy is to encourage researchers to develop practical ideas, useful research materials, and powerful technologies, often by providing financial support.

Our activities extend from exploratory biology to the identification and validation of therapeutic targets, and from drug discovery and development to clinical studies and trials.

About CHDI Management, Inc:

CHDI Management, Inc. was established in 2002 to provide administrative, management and grant making services to CHDI Foundation, Inc.

About our Donors

CHDI’s activities focus solely on the identification and development of drugs that delay or slow Huntington’s disease. We are indebted to our donors, whose generosity and guidance have made possible this exclusive focus on science.

For more information about CHDI, please go to www.chdifoundation.org

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