Science Director, Clinical “Wet” Biomarkers Discovery – Princeton, New Jersey
The position will be based in Princeton, N.J. with occasional travel to CHDI’s other offices in LA and NYC.
CHDI Management, Inc.
CHDI is a private, not-for-profit research organization. We work with an international network of scientists to discover drugs that slow the progression of Huntington’s Disease (HD). We seek to accelerate scientific progress by serving as a collaborative enabler. Our strategy is to encourage researchers to develop practical ideas, useful research materials, and powerful technologies, often by providing financial support. Our activities extend from exploratory biology to the identification and validation of therapeutic targets, and from drug discovery and development to clinical studies and trials.
Science Director, Clinical “Wet” Biomarkers Discovery
This position will report to the Unit Leader and will be responsible for “wet” (biofluid) biomarkers research in the clinical context of HD. This will include planning and supervision of biomarker projects, coordinating & managing experimental and observational clinical studies in HD, collaborating with our biorepository for sample collection required for translational biomarker discovery and validation.
The successful candidate will:
- Provide critical input in the design and supervision of translational biomarker studies
- Be able to independently design, plan and manage large single-/multi-site HD clinical studies through contract research organizations and academic/industrial collaborators
- Be able to provide critical input to data collection/analysis and quality control methods deployed in such studies
- Be responsible for providing scientific input and driving the creation of clinical documents required for the implementation, monitoring and evaluation of such clinical and translational studies.
- Review work produced by project team(s) and ensure that studies are conducted with scientific rigor and precision.
- Partner with Clinical Program Manager(s), legal and finance teams, and external collaborators to identify and resolve contracting issues related to HD clinical research in a timely manner and manage fiscal performance of the studies.
- Proactively contribute to ongoing scientific dialog for various Foundation programs.
- D. or Ph.D. degree in a biomedical area.
- At least 5 years of direct experience in clinical research in pharma/biotech or academic settings with focus on translational research in clinical settings.
- Good understanding of analysis principles for complex large data sets is preferred.
- Demonstrated knowledge of clinical study components and support functions.
- Knowledge of FDA and ICH regulations regarding Good Clinical Practice (GCP).
- Demonstrated record of self-motivation and problem-solving skills.
- CRO, contract management, and budgetary experience for clinical projects.
- Team oriented, excellent interpersonal skills, good written and oral communication skills.
Please send CVs to firstname.lastname@example.org