CHDI FOUNDATIONCHDI

Accelerating Therapeutic Development for Huntington's Disease

Director, Clinical Biorepository

Science Director, Clinical Biorepository

Job Location

The position will be based in Princeton, N.J. with occasional travel to CHDI’s other offices in LA and NYC.  Currently hybrid.

Other

Vaccination against COVID-19 is a prerequisite for employment at CHDI Management.

CHDI Management, Inc.

CHDI is a private, not-for-profit research organization. We work with an international network of scientists to discover drugs that slow the progression of Huntington’s Disease (HD). We seek to accelerate scientific progress by serving as a collaborative enabler. Our strategy is to encourage researchers to develop practical ideas, useful research materials, and powerful technologies, often by providing financial support. Our activities extend from exploratory biology to the identification and validation of therapeutic targets, and from drug discovery and development to clinical studies and trials.

Science Director, Clinical Biorepository

This position will report to the Unit Leader and will be responsible for biorepository related activities as well as biomarker verification testing in the clinical context of HD. This will include directing biorepository activities for sample collection and storage, planning and supervision of biomarker clinical study projects, and coordinating & managing experimental and observational clinical studies in HD.

The successful candidate will:

  • Provide scientific oversight of the biorepositories and manage biorepository operations including sample collection pipelines, sample processing, sample storage and tracking.
  • Be able to provide critical input to data collection/analysis and quality control methods deployed in biorepositories.
  • Provide critical input in the design and supervision of translational wet biomarker studies.
  • Be able to independently design, plan and manage large single-/multi-site HD clinical studies through contract research organizations and academic/industrial collaborators.
  • Be responsible for providing scientific input and driving the creation of clinical documents required for the implementation, monitoring and evaluation of such clinical and translational studies.
  • Partner with Clinical Program Manager(s), legal and finance teams, and external collaborators to identify and resolve contracting issues related to HD clinical research and biorepository use in a timely manner and manage fiscal performance of the biorepositories and studies.
  • Proactively contribute to ongoing scientific dialog for various Foundation programs.

Minimum Requirements:

  • MD. or Ph.D. degree in a biomedical area.
  • At least 5 years of direct experience in clinical research in pharma/biotech or academic settings with focus on biorepository operations and biosample collection and testing.
  • Good understanding of analysis principles for complex large data sets is preferred.
  • Demonstrated knowledge of clinical study components and support functions.
  • Knowledge of FDA and ICH regulations regarding Good Clinical Practice (GCP).
  • Demonstrated record of self-motivation and problem-solving skills.
  • CRO, contract management, and budgetary experience for clinical projects.
  • Team oriented, excellent interpersonal skills, good written and oral communication skills. Send resumes to